Practical synthesis of (3S,4S)-3-methoxy-4-methylaminopyrrolidine

Synthesis of 2,5-disubstituted pyrrolidines

Marianne Pichon, Bruno Figadère · Tetrahedron Asymmetry · 1996 · 232 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Pyrrole, pyrrolidine pyridine, piperidine, azepine and tropane alkaloids

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Pharmacy, Chemistry, Medicinal Chemistry +9

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Antimicrobial Agents and Chemotherapy · 1992 · 94 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Quinobenoxazines: A Class of Novel Antitumor Quinolones and Potent Mammalian DNA Topoisomerase II Catalytic Inhibitors

Paskasari A. Permana, Robert M. Snapka, Linus L. Shen et al. · Biochemistry · 1994 · 73 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives

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Medicine, Medicinal Chemistry, Pharmacology +10