The Journal of Antibiotics · 1991 · 98 citations · 15 references
MedicineMedicinal ChemistryPharmacologyAntimicrobial PharmacologyDrug DiscoveryParasitologyAnthelmintic PharmacologyAnthelmintic ResistanceAntiparasitic AgentsAntiparasitic PharmacologyAntiparasitic PharmacotherapyAntiparasitic TherapyAnthelmintic AgentsAnthelmintic Drug DevelopmentAnthelmintic Drug DiscoveryAnthelmintic TreatmentMechanisms Of Anthelmintic Action
Paraherquamide (1) an anthelmintic alkaloid, was isolated from a species of Penicillium along with three novel analogues 2, 3 and 4. Anthelmintic activity at least equal to that of paraherquamide is described for the 14-de-hydroxy compound, VM 54159 (4).
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The structure of paraherquamide, a toxic metabolite from
Mikio Yamazaki, Emi Okuyama, Makoto Kobayashi et al. · Tetrahedron Letters · 1981 · 202 citations
Pharmacy, Pharmacology, Toxicology +12