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Life SciencesCell BiologyPharmacologyApoptosisCancer PharmacologyCell SignalingApoptosis In CancerApoptosis PharmacologyApoptosis RegulationApoptosis ResistanceApoptotic SignalingBcl-2 Family ProteinsApoptosis TargetingNeuroblastoma BiologyPhosphatidylinositol 3-Kinase-akt Pathway
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In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations
Medicine, Oncology, Pharmacology +15
Amplification of a gene encoding a p53-associated protein in human sarcomas
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A small molecule–kinase interaction map for clinical kinase inhibitors
Miles A. Fabian, William Biggs, Daniel K. Treiber et al. · Nature Biotechnology · 2005 · 1.9K citations · Full text
The p53-mdm-2 autoregulatory feedback loop.
J. Henri Bayle, David C. Olson, Arnold J. Levine · Genes & Development · 1993 · 1.8K citations · Full text