Application of toxicogenomic tools in the drug research and development process

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

Da Wei Huang, Brad T. Sherman, Qina Tan et al. · Nucleic Acids Research · 2007 · 2.3K citations · Full text

Life Sciences, Bioinformatics, Biology +10

Application of a High-Content Multiparameter Cytotoxicity Assay to Prioritize Compounds Based on Toxicity Potential in Humans

Vivek C. Abraham, Danli L. Towne, Jeffrey F. Waring et al. · SLAS DISCOVERY · 2008 · 148 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

CEBS Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data

Michael D. Waters, Stanley Stasiewicz, B. Alex Merrick et al. · Nucleic Acids Research · 2007 · 148 citations · Full text

Life Sciences, Biochemistry, Toxicology +17

Developing and validating predictive decision tree models from mining chemical structural fingerprints and high–throughput screening data in PubChem

Lianyi Han, Yanli Wang, Stephen H. Bryant · BMC Bioinformatics · 2008 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

PROFILING OF GENE EXPRESSION IN RAT LIVER AND RAT PRIMARY CULTURED HEPATOCYTES TREATED WITH PEROXISOME PROLIFERATORS

Kotaro Tamura, Atsushi Ono, Toshikazu Miyagishima et al. · The Journal of Toxicological Sciences · 2006 · 69 citations · Full text

Pharmacy, Pharmacology, Toxicology +14