Concepedia

Transgenic Livestock as Bioreactors: Stable Expression of Human Alpha-1-Antitrypsin by a Flock of Sheep

Andrew S. Carver, Michael Dalrymple, Gordon Wright, D. Cottom, D. Reeves, Yvonne Gibson, Jayne L. Keenan, J. David Barrass, Ann R. Scott, Alan Colman,

Nature Biotechnology · 1993 · 91 citations · 17 references

DOI

Concepts

References

17

Establishment in culture of pluripotential cells from mouse embryos

Martin Evans, M. H. Kaufman · Nature · 1981 · 8.6K citations

, , +14

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +12

Position-independent, high-level expression of the human β-globin gene in transgenic mice

Frank Grosveld, Greet Blom van Assendelft, David R. Greaves et al. · Cell · 1987 · 2K citations · Full text

, , +6

Introns increase transcriptional efficiency in transgenic mice.

Ralph L. Brinster, J M Allen, Richard R. Behringer et al. · Proceedings of the National Academy of Sciences · 1988 · 736 citations · Full text

, , +16

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

Jon W. Gordon, Frank H. Ruddle · Science · 1981 · 685 citations

, , +13