Concepedia

Phase I dose-escalating study of panobinostat (LBH589) Administered intravenously to Japanese patients with advanced solid tumors

Sachi Morita, Satoshi Oizumi, Hironobu Minami, Koichi Kitagawa, Yoshito Komatsu, Yutaka Fujiwara, Megumi Inada, Satoshi Yuki, Naomi Kiyota, Ayako Mitsuma,

Investigational New Drugs · 2011 · 42 citations · 11 references

DOI

Concepts

References

11

A Phase I Study of Intravenous LBH589, a Novel Cinnamic Hydroxamic Acid Analogue Histone Deacetylase Inhibitor, in Patients with Refractory Hematologic Malignancies

Francis J. Giles, Thomas Fischer, Jörge E. Cortes et al. · Clinical Cancer Research · 2006 · 314 citations

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Radioembolization of Liver Metastases From Colorectal Cancer Using Yttrium-90 Microspheres With Concomitant Systemic Oxaliplatin, Fluorouracil, and Leucovorin Chemotherapy

Ricky A. Sharma, Guy A. Van Hazel, Bruno Morgan et al. · Journal of Clinical Oncology · 2007 · 312 citations · Full text

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EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

Günther Richter, Stephanie Plehm, Annette Fasan et al. · Proceedings of the National Academy of Sciences · 2009 · 308 citations · Full text

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EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma

Leah A. Owen, Ashley A. Kowalewski, Stephen L. Lessnick · PLoS ONE · 2008 · 152 citations · Full text

, , +16

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia

Mark Bishton, Simon J. Harrison, Benjamin Martin et al. · Blood · 2011 · 134 citations · Full text

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