Novel acetamidothiazole derivatives: Synthesis and in vitro anticancer evaluation

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Anne Monks, Dominic A. Scudiero, Philip Skehan et al. · JNCI Journal of the National Cancer Institute · 1991 · 3.3K citations

Medicine, Oncology, Pharmacology +11

Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen

Michael R. Boyd, Kenneth D. Paull · Drug Development Research · 1995 · 1.6K citations

Medicine, Oncology, Pharmacology +12

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

Kenneth D. Paull, Robert H. Shoemaker, Louis Hodes et al. · JNCI Journal of the National Cancer Institute · 1989 · 969 citations

Medicine, Biostatistics, Oncology +16

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

Xiaofeng Liu, Sisheng Ouyang, Biao Yu et al. · Nucleic Acids Research · 2010 · 947 citations · Full text

Pharmacy, Bioinformatics, Pharmacology +17