A novel mass spectrometry‐based method for determining insulin‐like growth factor 1: assessment in a cohort of subjects with newly diagnosed acromegaly

Abstract

uHPLC-MS/MS offers an independent method for determining/validating IGF-1 in subjects with acromegaly. Further studies, including the establishment of age- and sex-matched reference ranges and calibration to the new International IGF-1 standard IS 02/254, are now required to allow its introduction in to routine clinical use.