Exposure to Retinyl Esters, Retinol, and Retinoic Acids in Non-Pregnant Women following Increasing Single and Repeated Oral Doses of Vitamin A

Abstract

Repeated oral doses of up to 30,000 IU of vitamin A in addition to dietary vitamin A were without safety concern. Safe doses are probably higher, since plasma concentrations and exposure to RA remained at levels earlier shown to be without increased risk of teratogenicity in pregnant women.