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Evaluation of Azithromycin Resistance in Treponema pallidum Specimens From Madagascar

Kathleen Van Damme, Frieda Behets, Noro Lantoniaina Rosa Ravelomanana, Charmie Godornes, Maria R. Khan, Bodo Randrianasolo, Ny Lovaniaina Rabenja, Sheila A. Lukehart, Myron S. Cohen, Edward W. Hook

Sexually Transmitted Diseases · 2009 · 59 citations · 17 references

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Abstract

Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar.

References

17

1993 Sexually Transmitted Diseases Treatment Guidelines

Journal of School Health · 1994 · 923 citations

, , +17

Macrolide Resistance in<i>Treponema pallidum</i>in the United States and Ireland

Sheila A. Lukehart, Charmie Godornes, Barbara J. Molini et al. · New England Journal of Medicine · 2004 · 386 citations · Full text

, , +8

Clinical Experience With Penicillin Skin Testing in a Large Inner-City STD Clinic

J. Gadde · JAMA · 1993 · 340 citations

, , +17

Results of the National Institute of Allergy and Infectious Diseases Collaborative Clinical Trial to Test the Predictive Value of Skin Testing With Major and Minor Penicillin Derivatives in Hospitalized Adults

Dorothy D. Sogn · Archives of Internal Medicine · 1992 · 328 citations

, , +16

Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis

Gabriele Riedner, Mary Rusizoka, Jim Todd et al. · New England Journal of Medicine · 2005 · 297 citations · Full text

, , +10