Inhibition of prolyl oligopeptidase increases the survival of alpha-synuclein overexpressing cells after rotenone exposure by reducing alpha-synuclein oligomers

Parkinson disease: from pathology to molecular disease mechanisms

David T. Dexter, Peter Jenner · Free Radical Biology and Medicine · 2013 · 709 citations

Life Sciences, Neuroscience, Pathology +14

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

Ken Nakamura, Venu M. Nemani, Farnaz Azarbal et al. · Journal of Biological Chemistry · 2011 · 591 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Distinct Roles<i>In Vivo</i>for the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein

Darius Ebrahimi‐Fakhari, Ippolita Cantuti‐Castelvetri, Zhanyun Fan et al. · Journal of Neuroscience · 2011 · 373 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis

David W. Freeman, Rudy Orlando Cedillos, Samantha Choyke et al. · PLoS ONE · 2013 · 278 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The role of autophagy in Parkinson's disease: rotenone-based modeling

Nian Xiong, Jing Xiong, Min Jia et al. · Behavioral and Brain Functions · 2013 · 112 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17