A disulfide-linked conjugate of ferrocenyl chalcone and silicon(<scp>iv</scp>) phthalocyanine as an activatable photosensitiser

Abstract

A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.