Concepedia

Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin

Lori Buetow, Mads Gabrielsen, Nahoum G. Anthony, Hao Dou, Amrita Patel, H. Aitkenhead, Gary Sibbet, Brian O. Smith, Danny T. Huang

Molecular Cell · 2015 · 138 citations · 31 references

DOI

Concepts

References

31

Ubiquitin is phosphorylated by PINK1 to activate parkin

Fumika Koyano, Kei Okatsu, Hidetaka Kosako et al. · Nature · 2014 · 1.5K citations

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Lesley A. Kane, Michael Lazarou, Adam I. Fogel et al. · The Journal of Cell Biology · 2014 · 1.3K citations · Full text

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

Jijie Chai, Chunying Du, Jiawei Wu et al. · Nature · 2000 · 857 citations

, , +14

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay et al. · Biochemical Journal · 2014 · 815 citations · Full text

, , +16

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Jonathan N. Pruneda, Peter Littlefield, Sarah E. Soss et al. · Molecular Cell · 2012 · 341 citations · Full text

, , +15