Immunohistochemical detection of P53 overexpression in paraffin wax-embedded squamous cell carcinomas of cattle, horses, cats and dogs

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

S M Hsu, Laurence Raine, Herbert Fanger · Journal of Histochemistry & Cytochemistry · 1981 · 14.3K citations · Full text

Life Sciences, Immunology, Immunopathology +8

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey et al. · Science · 1994 · 2.5K citations

Life Sciences, Molecular Biology, Oncology +16

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

Medicine, Genetics, Molecular Genetics +12

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Douglas E. Brash, Jeffrey A. Rudolph, J A Simon et al. · Proceedings of the National Academy of Sciences · 1991 · 2K citations

Medicine, Genetics, Oncology +17

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

Cathy A. Finlay, Philip W. Hinds, Tse‐Hua Tan et al. · Molecular and Cellular Biology · 1988 · 1.1K citations · Full text

Medicine, Genetics, Molecular Biology +14