Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex - Concepedia

Concepedia

Publication | Open Access

Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex

DOI Full Paper Access

42

Citations

17

References

2010

Year

Michelle Bond, Chad M. Whitman, Jennifer J. Kohler

Molecular BioSystems

Microbial ToxinProtein AssemblyPhotochemistryBiochemistryNatural SciencesPhotobiologyGlycobiologyBiotechnologyMolecular BiologySialic AcidPhototoxicityBioconjugationBiomolecular InteractionMicrobiologyGanglioside Gm1MedicinePhotodegradationBio-orthogonal Chemistry

Abstract

When photoirradiated, an unnatural sialic acid analog can covalently capture the complex formed by ganglioside GM1 and cholera toxin subunit B.

References

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