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1046 FIRST-IN-MAN DEMONSTRATION OF POTENT ANTIVIRAL ACTIVITY WITH A NUCLEOSIDE POLYMERASE (R7128) AND PROTEASE (R7227/ITMN-191) INHIBITOR COMBINATION IN HCV: SAFETY, PHARMACOKINETICS, AND VIROLOGIC RESULTS FROM INFORM-1

Antiviral AgentsViral Polymerase StructureMedicineAntiviral Drug DevelopmentAntiviral TherapyHepatitisVirologyAntiviral DrugPharmacologyAntiviral CompoundViral Immunity