Concepedia

A novel antitumor compound, NC-190, induces topoisomerase II-dependent DNA cleavage and DNA fragmentation

Takaki Yamagishi, Shiro Nakaike, Tomotake Ikeda, Hisao Ikeya, Susumu Otomo

Cancer Chemotherapy and Pharmacology · 1996 · 21 citations · 15 references

DOI

Concepts

References

15

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

Michael C. Alley, Dominic A. Scudiero, Anne Monks et al. · PubMed · 1988 · 3.1K citations

, , +14

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

, , +17

Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

Scott H. Kaufmann · PubMed · 1989 · 934 citations

, , +16

Cleavage of DNA by mammalian DNA topoisomerase II.

Leroy F. Liu, Thomas C. Rowe, K M Tewey et al. · Journal of Biological Chemistry · 1983 · 533 citations · Full text

, , +13

Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.

P. Roy Walker, Carl Smith, T. Youdale et al. · PubMed · 1991 · 384 citations

, , +15