Serum Levels of Free 1,25-Dihydroxyvitamin D in Vitamin D Toxicity

Abstract

Although the patients had normal or near-normal total 1,25-(OH)2D values, most patients had elevated free 1,25-(OH)2D levels. These findings suggest that elevated free 1,25-(OH)2D levels might play a role in the pathogenesis of hypercalcemia in vitamin D toxicity.