Thiosemicarbazones active against Clostridium difficile

Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Xiaohui Du, Chun Guo, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2002 · 383 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against <i>Plasmodium falciparum</i>, <i>Trypanosoma brucei</i>, and <i>Trypanosoma cruzi</i>

Doron C. Greenbaum, Zachary B. Mackey, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2004 · 254 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel Antitrypanosomal Agents Based on Palladium Nitrofurylthiosemicarbazone Complexes:  DNA and Redox Metabolism as Potential Therapeutic Targets

Lucı́a Otero, Marisol Vieites, Lucı́a Boiani et al. · Journal of Medicinal Chemistry · 2006 · 168 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones

Gabriela Aguirre, Lucı́a Boiani, Hugo Cerecetto et al. · Bioorganic & Medicinal Chemistry · 2004 · 132 citations · Full text

Veterinary Medicine, Infectious Diseases, Medicinal Chemistry +11

Emergence and Control of Fluoroquinolone-Resistant, Toxin A–Negative, Toxin B–Positive<i>Clostridium difficile</i>

Denise Drudy, N Harnedy, Séamus Fanning et al. · Infection Control and Hospital Epidemiology · 2007 · 126 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +17