Direct Asymmetric Aldol Reactions of Acetone Using Bimetallic Zinc Catalysts

Barry M. Trost, Elliad R. Silcoff, Hisanaka Ito

Organic Letters · 2001 · 162 citations · 9 references

Concepts

Abstract

[reaction: see text] The enantioselective aldol reaction using a novel binuclear zinc catalyst of acetone with several aldehydes gave products in good yields (62-89%) with a high level of enantioselectivity (ee = 76-92%).

References

9