Hydrogen peroxide negatively modulates Wnt signaling through downregulation of β-catenin

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick · Nature · 1999 · 3.6K citations

Cancer Research, Oncology, Colon Carcinoma Cells +10

The Biology of Oxygen Radicals

Irwin Fridovich · Science · 1978 · 3.3K citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

Tcf Reporter Gene, Pathology, Cancer Biology +18

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

Tumor Biology, Signaling Pathway, Gene Expression Profile +15

Functional interaction of β-catenin with the transcription factor LEF-1

Jürgen Behrens, Jens Peter von Kries, Michael Kühl et al. · Nature · 1996 · 2.9K citations

Transcriptional Regulation, Signaling Pathway, Molecular Regulation +8