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Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

Lori A. Kohlstaedt, J Wang, Jonathan M. Friedman et al. · Science · 1992 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +17

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

David W. Cushman, H.S. Cheung, Emily F. Sabo et al. · Biochemistry · 1977 · 901 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence.

H.S. Cheung, F.L. Wang, Miguel A. Ondetti et al. · Journal of Biological Chemistry · 1980 · 746 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A new class of angiotensin-converting enzyme inhibitors

Arthur A. Patchett, Elbert E. Harris, Edward W. Tristram et al. · Nature · 1980 · 706 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation In Animal Cells

Guy L. James, Joseph L. Goldstein, Michael S. Brown et al. · Science · 1993 · 629 citations

Medicine, Oncology, Pharmacology +15