Concepedia

The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease

Marong Fang, Jing Wang, Xiaobing Zhang, Yu Geng, Zhiying Hu, John A. Rudd, Shucai Ling, Wei Chen, Shu Han

Toxicology Letters · 2011 · 212 citations · 36 references

DOI

Concepts

References

36

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

, , +17

Identification of Tissue-Specific MicroRNAs from Mouse

Mariana Lagos‐Quintana, Reinhard Rauhut, Abdullah Yalçın et al. · Current Biology · 2002 · 3.3K citations · Full text

, , +10

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

Bruce A. Yankner, Lawrence K. Duffy, Daniel A. Kirschner · Science · 1990 · 2K citations

, , +17

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Eugene V. Makeyev, Jiangwen Zhang, Mónica A. Carrasco et al. · Molecular Cell · 2007 · 1.4K citations · Full text

, , +14

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression

Sébastien S. Hébert, Katrien Horré, Laura Nicolaï et al. · Proceedings of the National Academy of Sciences · 2008 · 1.2K citations · Full text

, , +15