Ocular changes in limited forms of Wegener's granulomatosis.

Abstract

Eight patients who had limited forms of Wegener's granulomatosis are described, with details of their pathology. Ocular pathological data were available for 2 of them. The condition carries a serious ocular risk; useful vision was lost in 6 out of 16 eyes (37%). An indolent but slowly progressive marginal keratitis and scleritis was a prominent feature in 4 patients and was helpful in suggesting the diagnosis. Limited froms of Wegener's granulomatosis carry a better prognosis and response to treatment than the classical disease.