Ageing-associated 5 kb deletion in human liver mitochondrial DNA

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

Natural Sciences, Chemistry, Aging +16

The Biology of Oxygen Radicals

Irwin Fridovich · Science · 1978 · 3.3K citations

Life Sciences, Biochemistry, Molecular Biology +14

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation

John M. Shoffner, Marie T. Lott, Angela Maria Serena Lezza et al. · Cell · 1990 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +16

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

AnthonyW. Linnane, Takayuki Ozawa, S Marzuki et al. · The Lancet · 1989 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +12