Japanese Journal of Applied Physics · 2013 · 15 citations · 9 references
EngineeringBioengineeringBiomedical EngineeringAcousticsBiomemsBiosensorsAcoustic SensingAcoustic Sensing SystemsAcoustic SensorsBiomedical SensorsBiosensors For Immune DetectionClinical BiosensingBiosensor CharacterizationExperimental Results InterpretationLoading EffectQuartz Crystal Microbalance BiosensorsSurface Acoustic Wave BiosensorsSurface Acoustic Wave SensorsViscosity
A numerical analysis of a shear horizontal surface acoustic wave (SH-SAW) immunoassay biosensor has been investigated. The numerical calculation method proposed by Campbell and Jones has generally been used to calculate SAW propagation characteristics. In this paper, a numerical calculation method for SH-SAW propagation characteristics, which is a modified method of Campbell and Jones involving the effect of liquid viscosity is applied to quartz. A mass loading sensitivity of a 250 MHz SH-SAW delay-line biosensor was calculated and compared with the experimental results. It can be concluded from the results that viscosity sensitivity is dominant over mass loading sensitivity for 250 MHz SH-SAW biosensors.
9