Concepedia

Publication | Open Access

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

DOIFull Paper Access

144

Citations

56

References

2012

Year

Ying Sun, Yoon Lim, Fang Li, Shen Liu, Jianjun Lu, Rainer Haberberger, Jinhua Zhong, Xin‐Fu Zhou
PLoS ONE

Abstract

proBDNF has an opposing role in neurite outgrowth to that of mature BDNF. Our observations suggest that proBDNF collapses neurites outgrowth and filopodial growth cones by activating RhoA through the p75NTR signaling pathway.

References

YearCitations

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