Studies on the formation of Cu(II) and Ni(II) complexes of l,2-dihydroxy-9,10-anthraquinone and lack of stimulated superoxide formation by the complexes

A clinicopathologic analysis of adriamycin cardiotoxicity

Edward A. Lefrak, Jan Piťha, Sidney Rosenheim et al. · Cancer · 1973 · 1.6K citations

Medicine, Cardiology, Pharmacology +16

Effect of anthracycline antibiotics on oxygen radical formation in rat heart.

James H. Doroshow · PubMed · 1983 · 629 citations

Life Sciences, Biochemistry, Pharmacology +17

Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.

Makoto Inaba, Harumi Kobayashi, Yoshio Sakurai et al. · PubMed · 1979 · 454 citations

Medicine, Oncology, Pharmacology +17

Adriamycin—A Review

Stephen K. Carter · JNCI Journal of the National Cancer Institute · 1975 · 454 citations · Full text

Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen.

Vivian Berlin, William A. Haseltine · Journal of Biological Chemistry · 1981 · 280 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17