Overexpression of Caspase-1 in Aorta of Patients with Coronary Atherosclerosis

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.9K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

Kristiina Rajamäki, Jani Lappalainen, Katariina Öörni et al. · PLoS ONE · 2010 · 1K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

Hirokazu Kirii, Tamikazu Niwa, Yasuhiro Yamada et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2003 · 739 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Transesophageal echocardiographically detected atherosclerotic aortic plaque is a marker for coronary artery disease

Gary P. Fazio, Rita F. Redberg, Timothy M. Winslow et al. · Journal of the American College of Cardiology · 1993 · 259 citations

Medicine, Cardiology, Radiology +14

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

Philippe Menu, Maxime Pellegrin, J-F Aubert et al. · Cell Death and Disease · 2011 · 244 citations · Full text

Life Sciences, Immunology, Pathology +17