Histamine release from Weibel‐Palade bodies of toad aortas induced by endothelin‐1 and sarafotoxin‐S6b

Abstract

The present study clearly shows that ET-1 and STX induce the histamine release from WP bodies of the toad aortas by means of HPLC and immunoelectron microscopy. Histamine discharged from the WP bodies may be involved in the vasocontraction evoked by ET-1 and STX.