Concepedia

A Mouse Model with Liver-Specific Deletion and Global Suppression of the NADPH-Cytochrome P450 Reductase Gene: Characterization and Utility for in Vivo Studies of Cyclophosphamide Disposition

Jun Gu, Chong-Sheng Chen, Yuan Wei, Cheng Fang, Fang Xie, Kurunthachalam Kannan, Weizhu Yang, David J. Waxman, Xinxin Ding

Journal of Pharmacology and Experimental Therapeutics · 2007 · 26 citations · 28 references

DOI

References

28

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

Catherine Postic, Masakazu Shiota, Kevin D. Niswender et al. · Journal of Biological Chemistry · 1999 · 1.3K citations · Full text

Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms

T D Porter, Minor J. Coon · Journal of Biological Chemistry · 1991 · 679 citations · Full text

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An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

William F. Greenlee, Alan Poland · Journal of Pharmacology and Experimental Therapeutics · 1978 · 624 citations

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

Raija L.P. Lindberg, Masahiko Negishi · Nature · 1989 · 384 citations

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