A high-throughput assay for assessing the cell permeability of combinatorial libraries

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.8K citations

Health Sciences, Medicine, Physiology +9

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

Molecular Biology, Small Molecule Inhibitor, Cytoskeleton +18

Cell-penetrating Peptides

Jean‐Philippe Richard, Kamran Melikov, Éric Vivès et al. · Journal of Biological Chemistry · 2002 · 1.4K citations · Full text

Flow Cytometry Analysis, Cell Fixation, Biochemistry +12

Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis

Ronald N. Zuckermann, Janice M. Kerr, Stephen B. H. Kent et al. · Journal of the American Chemical Society · 1992 · 1.2K citations

Combinatorial Chemistry, Bioorganic Chemistry, Efficient Method +18

Residue-based control of helix shape in β-peptide oligomers

Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein et al. · Nature · 1997 · 621 citations

Protein Assembly, Helix Shape, Natural Sciences +3