Selective attenuation of μ-opioid receptor-mediated effects in rat sensory neurons by intrathecal administration of antisense oligodeoxynucleotides

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

T L Yaksh, Thomas A. Rudy · Journal of Pharmacology and Experimental Therapeutics · 1977 · 554 citations

Medicine, Anesthesiology, Pharmacology +12

Activation of μ opioid receptors inhibits transient high- and low-threshold Ca 2+ currents, but spares a sustained current

Jean E. Schroeder, P.S. Fischbach, Dali Zheng et al. · Neuron · 1991 · 203 citations

Life Sciences, Neurobiology, Pharmacology +13

Selective loss of δ opioid analgesia and binding by antisense oligodeoxynucleotides to a δ opioid receptor

Kelly M. Standifer, Chih‐Cheng Chien, Claes Wahlested et al. · Neuron · 1994 · 198 citations

Medicine, Pharmacology, Molecular Pharmacology +16

Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro

Michael S. Gold, S. Dastmalchi, Jon D. Levine · Neuroscience · 1996 · 188 citations

Life Sciences, Neurobiology, Neuroscience +16

Involvement of the mu-opiate receptor in peripheral analgesia

Jon D. Levine, Yetunde O. Taiwo · Neuroscience · 1989 · 168 citations

Medicine, Pharmacology, Neuropharmacology +13