A concise synthesis of the bioactive meroterpenoid natural product (±)-liphagal, a potent PI3K inhibitor

Liphagal, a Selective Inhibitor of PI3 Kinase α Isolated from the Sponge <i>Aka </i><i>c</i><i>oralliphaga</i>:  Structure Elucidation and Biomimetic Synthesis

Frédéric Marion, David E. Williams, Brian O. Patrick et al. · Organic Letters · 2005 · 155 citations

Natural Sciences, Biochemistry, Medicinal Chemistry +16

Enantio- and Diastereoselective Stepwise Cyclization of Polyprenoids Induced by Chiral and Achiral LBAs. A New Entry to (−)-Ambrox, (+)-Podocarpa-8,11,13-triene Diterpenoids, and (−)-Tetracyclic Polyprenoid of Sedimentary Origin

Kazuaki Ishihara, Hideaki Ishibashi, Hisashi Yamamoto · Journal of the American Chemical Society · 2002 · 129 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +7

Drugs from the deep

Emma Marris · Nature · 2006 · 83 citations · Full text

Medicine, Pharmacology, Drug Discovery +1

Synthesis of (±)-Ambrox from (<i>E</i>)-Nerolidol and β-Ionone <i>via</i> Allylic Alcohol [2,3] Sigmatropic Rearrangement

Alejandro F. Barrero, Joaquı́n Altarejos, Enrique Álvarez‐Manzaneda et al. · The Journal of Organic Chemistry · 1996 · 53 citations

Natural Sciences, Chemistry, Organic Chemistry +4

A total synthesis of (±)-frondosins A and B

Goverdhan Mehta, N.S. Likhite · Tetrahedron Letters · 2008 · 33 citations

Natural Sciences, Biochemistry, Chemistry +4