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Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind, placebo-controlled Phase IIa study

Alejandra Guillermina Miranda‐Díaz, Luis Miguel Román-Pintos, Adolfo Daniel Rodríguez-Carrizález, Rogelio Troyo‐Sanromán, María del Pilar Alatorre-Carranza, Ernesto Germán Cardona-Muñóz, Jaimie Hernandez-Ojeda

Diabetes Metabolic Syndrome and Obesity · 2014 · 43 citations · 21 references

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Abstract

The severity, symptoms, and nerve conduction parameters of DPN improved after 12 weeks of treatment with rosuvastatin. These beneficial effects appear to be attributable to reductions in lipid peroxidation and oxidative stress.

References

21

Biochemistry and molecular cell biology of diabetic complications

Michael Brownlee · Nature · 2001 · 8.9K citations

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Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy

Dan Ziegler, P. James B. Dyck, Irina Gurieva et al. · Diabetes Care · 2006 · 536 citations · Full text

HMG-CoA Reductase Inhibitors Improve Endothelial Dysfunction in Normocholesterolemic Hypertension via Reduced Production of Reactive Oxygen Species

Ulrich Laufs, Anselm T. Bäumer, Kirsten Müller et al. · Hypertension · 2001 · 458 citations · Full text

Statins Promote Potent Systemic Antioxidant Effects Through Specific Inflammatory Pathways

Mehdi H. Shishehbor, Marie-Luise Brennan, Ronnier J. Aviles et al. · Circulation · 2003 · 403 citations

Diabetes and Alpha Lipoic Acid

Saeid Golbidi, Mohammad Badran, Ismail Laher · Frontiers in Pharmacology · 2011 · 270 citations · Full text