Hypocretin (orexin) loss in Alzheimer's disease

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience · 1998 · 3.5K citations · Full text

Medicine, Neurobiology, Neuroscience +14

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron, Juliette Faraco, William M. Rogers et al. · Nature Medicine · 2000 · 2.1K citations

Life Sciences, Neurology, Neuroscience +13

The Role of Cerebrospinal Fluid Hypocretin Measurement in the Diagnosis of Narcolepsy and Other Hypersomnias

Emmanuel Mignot, Gert Jan Lammers, Beth Ripley et al. · Archives of Neurology · 2002 · 1.1K citations

Medicine, Neurology, Psychiatry +16

Distribution of orexin neurons in the adult rat brain

Tadahiro Nambu, Takeshi Sakurai, Katsuyoshi Mizukami et al. · Brain Research · 1999 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +9

Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease

W. Witting, I.H. Kwa, Piet Eikelenboom et al. · Biological Psychiatry · 1990 · 633 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12