Archives of Disease in Childhood · 1976 · 320 citations · 9 references
MedicineNephrologyPediatricsPediatric NephrologyRenal PathophysiologyRenal PharmacokineticsGlomerular FiltrationRenal AssessmentRenal ClearanceRenal Function TestingRenal Function TestsRenal Impairment24-Hour Urine Collection24-Hour Urine Creatinine ClearanceBody Surface Area CalculationCreatinine Clearance FormulasEstimated Creatinine ClearanceGlomerular Filtration Rate AssessmentGlomerular Filtration Rate MeasurementPediatric Creatinine Clearance
The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).
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Delafield Du Bois · Archives of internal medicine · 1916 · 4.3K citations
Medicine, Pediatrics, Physiology +15
Statistical Methods in Medical Research
Peter A. Lachenbruch, P. Armitage · Technometrics · 1972 · 1.6K citations