Are hyperostosis frontalis interna and leptin linked? A hypothetical approach about hormonal influence on human microevolution

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.8K citations

Life Sciences, Biochemistry, Endocrinology +12

The Expensive-Tissue Hypothesis: The Brain and the Digestive System in Human and Primate Evolution

Leslie C. Aiello, P.E. Wheeler · Current Anthropology · 1995 · 2.3K citations

Life Sciences, Evolutionary Biology, Neuroscience +16

Leptin Inhibits Bone Formation through a Hypothalamic Relay

Patricia Ducy, Michael Amling, Shu Takeda et al. · Cell · 2000 · 2.1K citations · Full text

Medicine, Endocrinology, Physiology +13

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

Kenn Holmbeck, Paolo Bianco, John J. Caterina et al. · Cell · 1999 · 1.3K citations · Full text

Medicine, Pathobiology, Pathology +12