Chrono-coherent imaging for medicine

Abstract

We describe a new method for imaging with visible and near visible light inside media, such as tissues, which have strong light scattering. The chrono-coherent imaging (CCI) method is demonstrated in this paper for a transmission geometry where an absorbing object is completely hidden from normal visual observation by light scattering of the media. The resultant images are most similar to X rays, with cumulative transmission showing absorption features and refractive index differences in the media. We discuss laser coherence properties, coherence measurements, the relation of CCI to light-inflight holography, holographic film properties relevant to CCI, a particular optical setup for CCI, the results of a demonstration experiment imaging an absorbing object hidden by light scattering, and an experiment to estimate the clinical applicability of CCI.