Involvement of Nitric Oxide and Hyperbaric Oxygen in the Pathogenesis of Cyclophosphamide Induced Hemorrhagic Cystitis in Rats

Abstract

Nitric oxide produced by inducible nitric oxide synthase is an important mediator in the pathogenesis of cyclophosphamide induced cystitis. Hyperbaric oxygen has a beneficial effect on repairing bladder damage rather than on bladder protection.