Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

Livia Casciola‐Rosen, Grant J. Anhalt, Antony Rosen · The Journal of Experimental Medicine · 1994 · 1.7K citations · Full text

Life Sciences, Cell Biology, Immunology +15

Systemic Lupus Erythematosus

Anisur Rahman, David Isenberg · New England Journal of Medicine · 2008 · 1.6K citations

Life Sciences, Immunology, Nephrology +17

Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

Jane Tian, Ana M. Avalos, Su-Yau Mao et al. · Nature Immunology · 2007 · 1.4K citations

Life Sciences, Immunology, Molecular Biology +12

Human lupus autoantibody–DNA complexes activate DCs through cooperation of CD32 and TLR9

Terry K. Means, Eicke Latz, Fumitaka Hayashi et al. · Journal of Clinical Investigation · 2005 · 828 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Induction of interferon‐α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG

Tanja Lövgren, Maija‐Leena Eloranta, Ullvi Båve et al. · Arthritis & Rheumatism · 2004 · 551 citations

Life Sciences, Cell Biology, Immunology +15