A rapid, microwave-assisted, one-pot cyclopropanation reaction to synthesize (4-ferrocenyl)benzoylcyclopropane in the solid state

Abstract

Some new (4-ferrocenyl)benzoylcyclopropanes were prepared rapidly via a microwave-assisted, one-pot cyclopropanation reaction in the solid state, directly using 4-ferrocenylacetophenone, aldehyde, and sulfur ylide as the starting materials. The main advantages of this procedure are convenient operation, shorter reaction time, lower environmental pollution, and no need to isolate the intermediate product (chalcone) in a separate step.Key words: 4-ferrocenylacetophenone, sulfur ylide, microwave-assisted, one-pot, solid state.