The −491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEϵ4 allele and Alzheimer's Disease

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Suzanne S. Mirra, Albert Heyman, Daniel W. McKeel et al. · Neurology · 1991 · 5.1K citations

Medicine, Genetics, Neurology +17

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1993 · 1.5K citations · Full text

Life Sciences, Genetics, Neuroscience +17

Very Old Women at Highest Risk of Dementia and Alzheimer's Disease

Laura Fratiglioni, Matti Viitanen, Eva von Strauss et al. · Neurology · 1997 · 553 citations

Medicine, Geriatric Medicine, Dementia +14

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia

María J. Bullido, María J. Artiga, Marı́a Recuero et al. · Nature Genetics · 1998 · 287 citations

Medicine, Genetics, Molecular Genetics +12