The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury

Ryan M. McAdams, Sandra E. Juul

Neurology Research International · 2012 · 154 citations · 102 references

DOIFull text

Open access

Concepts

Abstract

Perinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the common pathways associated with perinatal brain injury induced by a variety of insults, such as hypoxic-ischemic injury, reperfusion injury, toxin-mediated injury, and infection. This paper examines our current knowledge regarding cytokine-related perinatal brain injury and specifically discusses strategies for attenuating cytokine-mediated brain damage.

References

102