Hemodialysis and L-arginine, but not D-arginine, correct renal failure-associated endothelial dysfunction

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

Uttam Garg, Aviv Hassid · Journal of Clinical Investigation · 1989 · 2.2K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +12

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

A. Leone, S. Moncada, Patrick Vallance et al. · The Lancet · 1992 · 2.1K citations

Medicine, Nephrology, Pharmacology +11

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

Patrick Vallance, Joe Collier, Salvador Moncada · The Lancet · 1989 · 1.6K citations

Life Sciences, Internal Medicine, Physiology +5

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.4K citations

Life Sciences, Biochemistry, Physiology +9