A Small Molecule Screen Identifies Selective Inhibitors of Urea Transporter UT-A

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Association between Water Intake, Chronic Kidney Disease, and Cardiovascular Disease: A Cross-Sectional Analysis of NHANES Data

Jessica M. Sontrop, Stephanie N. Dixon, Amit X. Garg et al. · American Journal of Nephrology · 2013 · 5.9K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +15

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan B. Baell, Georgina A. Holloway · Journal of Medicinal Chemistry · 2010 · 3.9K citations

Pharmacy, Biochemistry, Analytical Chemistry +14

FRED Pose Prediction and Virtual Screening Accuracy

Mark McGann · Journal of Chemical Information and Modeling · 2011 · 769 citations

Pharmacy, Biostatistics, Drug Discovery +16

Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

Lars Lannfelt, Kaj Blennow, Henrik Zetterberg et al. · The Lancet Neurology · 2008 · 712 citations

Medicine, Neuroscience, Pharmacology +17