Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

H. Bernheimer, W Birkmayer, Oleh Hornykiewicz et al. · Journal of the Neurological Sciences · 1973 · 2.7K citations

Life Sciences, Neurology, Neuroscience +16

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson's Disease

Stephen J. Kish, Kathleen Shannak, Oleh Hornykiewicz · New England Journal of Medicine · 1988 · 2K citations

Medicine, Neuroscience, Neurosurgery +17

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Vernice Jackson‐Lewis, Michael W. Jakowec, Robert E. Burke et al. · Neurodegeneration · 1995 · 608 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats

Terry E. Robinson, Ian Q. Whishaw · Brain Research · 1988 · 517 citations

Life Sciences, Neuroscience, Pharmacology +17