Concepedia

Convenient Conversion of<i>cis</i>-Homoallylic Alcohols into Corresponding Bromides with Ph<sub>3</sub>PBr<sub>2</sub>

Jacqueline Sandri, Jacques Viala

Synthetic Communications · 1992 · 29 citations · 17 references

DOI

Concepts

Abstract

Abstract An mild and easy worked up procedure using the cheap reagent Ph3PBr2 allowed us to improve the conversion of sensitive alcohols (homoallylic and acetalized) into their corresponding bromides in high yields.

References

17

Studies in Organophosphorus Chemistry. I. Conversion of Alcohols and Phenols to Halides by Tertiary Phosphine Dihalides

Germany Wiley, Robert Lenard Hershkowitz, Burton Maxwell Rein et al. · Journal of the American Chemical Society · 1964 · 282 citations

, , +5

The total synthesis of 12-HETE (12-hydroxyeicosatetraenoic acid) and 12,20-diHETE

Yves Leblanc, Brian J. Fitzsimmons, Julian J. Adams et al. · The Journal of Organic Chemistry · 1986 · 98 citations

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The structure of triphenylphosphorus–dibromine, the first crystallographically characterised bromophosphorane, a compound which has the novel four-coordinate molecular Ph<sub>3</sub>P–Br–Br geometry

Neil Bricklebank, Stephen M. Godfrey, Anthony G. Mackie et al. · Journal of the Chemical Society Chemical Communications · 1992 · 54 citations

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1,2-bis(diphenylphosphino)ethane tetrahalide: A convenient reagent for the conversion of alcohols to the corresponding halides

Steven P. Schmidt, Dee W. Brooks · Tetrahedron Letters · 1987 · 49 citations

, , +4

Total synthesis of LTB4 and analogs

Yvan Guindon, Daniel Delorme, Cheuk K. Lau et al. · The Journal of Organic Chemistry · 1988 · 45 citations

, , +7