ASBESTOSIS ASSOCIATED WITH BRONCHOGENIC CARCINOMA

Abstract

HOLLEB and Angrist¹in 1942 reported two cases of bronchogenic carcinoma in association with pulmonary asbestosis. The first case of carcinoma of the lung in association with pulmonary asbestosis was reported in 1935 by Lynch and Smith.²In that year Gloyne reported two cases and in 1936 another.³Egbert and Geiger⁴reported one case in 1936. Nordmann⁵presented two cases in 1938. One year later Lynch and Smith⁶added another. Of these, six were of squamouscell carcinoma, one of squamous-cell carcinoma with glandular features, two of oat-cell carcinoma, one of glandular carcinoma, and another of squamous-cell nonkeratinizing carcinoma. The age of the patients ranged from 35 to 71 years, and the duration of exposure, from 19 months to 25 years. All but two had metastases. Freedom from exposure before death varied from four months to 15 years. We have found four additional cases not mentioned in the