Journal of Veterinary Medical Science · 2011 · 19 citations · 9 references
Veterinary MedicinePathologyVeterinary PathologyCellular PathologyMetastasisTumor PathologyCutaneous LymphomaCutaneous NeoplasmsLymphoid NeoplasmsLymphoid Tissue PathologyLymphoid TumorsNeoplastic PathologyCanine LymphomaCanine Tumor PathologyExtramedullary PlasmacytomaFeline Tumor PathologyLymphoid Neoplasm DiagnosisLymphoma HistopathologyLymphomatoid Cutaneous MetastasisLymphoplasmacytic Lymphoma
A lymphoplasmacytic lymphoma was diagnosed in a 12- year-old domestic cat that had a primary cutaneous mass involving the stomach, liver, kidneys, heart, abdominal wall, diaphragm, bone marrow and several lymph nodes. Histopathologically, the most characteristic feature of this tumor was the heterogeneity of cell components, such as small lymphocytes, well-differentiated plasma cells and plasmacytoid transformed lymphocytes. Amyloid was deposited in the skin, stomach, and several lymph nodes. Immunohistochemically, neoplastic small lymphocytes were positive for CD20, and well-differentiated plasma cells and plasmacytoid transformed lymphocytes were positive for λ-Ig light chains and MUM1/IRF-4. These results emphasize the importance of lymphoplasmacytic lymphoma as a differential diagnosis of extramedullary cutaneous plasmacytoma in cats.
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Prognostic Value of Histopathological Grading in Canine Extramedullary Plasmacytomas
Siegfried Platz, W. Breuer, S. Pfleghaar et al. · Veterinary Pathology · 1999 · 82 citations
Amyloidomas of the nervous system
R. Hubert Laeng, Hans J�rg Altermatt, Bernd W. Scheithauer et al. · Cancer · 1998 · 78 citations